Description

2-Bromo-4-Chloro-1-Fluorobenzene is a high-purity halogenated benzene derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), liquid crystal materials, and specialty fine chemicals who require reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogen substituents for bioactivity.
• Liquid Crystal Materials: Serves as a core structure in the development of fluorinated liquid crystals for display technologies.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and host materials in OLED devices.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers and advanced organic frameworks.

Basic Information

Product Name	2-Bromo-4-Chloro-1-Fluorobenzene
CAS No.	1996-30-1
Molecular Formula	C6H3BrClF
Molecular Weight	209.44 g/mol
Synonyms	1-Bromo-3-Chloro-4-Fluorobenzene; 4-Chloro-2-Bromofluorobenzene; 2-Bromo-4-chlorofluorobenzene; 3-Chloro-4-fluorobromobenzene; Benzene, 2-bromo-4-chloro-1-fluoro-; 4-Fluoro-2-bromochlorobenzene; 2-Bromo-4-chloro-1-fluorobenzene; 3-Chloro-4-fluorophenyl bromide
EINECS	217-900-8

Quality Control

Every batch of 2-Bromo-4-Chloro-1-Fluorobenzene is manufactured under strict quality management systems. We employ advanced analytical techniques including GC, HPLC, and NMR to ensure high purity and batch-to-batch consistency, meeting the stringent requirements of fine chemical and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Density (at 20°C)	~1.7 g/cm³
Boiling Point	~205-207 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.