Description

Ethylglyoxal Bis(Guanylhydrazone) is a specialized guanylhydrazone derivative with significant biochemical activity. This compound is valued for its role as a potent inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC), a key enzyme in the polyamine biosynthesis pathway. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life sciences sectors for developing therapeutic agents and conducting biochemical studies related to cell proliferation and cancer research.

Application

• Biochemical Research: Used as a specific inhibitor of S-adenosylmethionine decarboxylase (AdoMetDC) in enzymatic and cellular studies.
• Pharmaceutical Intermediates: Serves as a key building block in the synthesis of novel therapeutic compounds targeting polyamine metabolism.
• Oncology Research: Investigated for its potential anti-proliferative effects in cancer cell lines and preclinical models.
• Life Science Reagents: Employed in the formulation of high-purity biochemical reagents and assay kits.
• Academic & Industrial R&D: A critical tool for universities and biotech companies exploring polyamine biology and related disease mechanisms.

Basic Information

Product Name	Ethylglyoxal Bis(Guanylhydrazone)
CAS No.	1945-68-2
Molecular Formula	C6H14N8
Molecular Weight	198.23 g/mol
Synonyms	Ethylglyoxal Bis(Guanylhydrazone); EGBC; 1,1'-[(1E,1'E)-Ethane-1,2-diylidenedihydrazin-2-yl-1-ylidene]diguanidine; NSC 32946; AdoMetDC Inhibitor; S-Adenosylmethionine Decarboxylase Inhibitor; Ethylglyoxal Bis(Amidinohydrazone); Bis(guanylhydrazone) of Ethylglyoxal
EINECS	Contact for details

Quality Control

Our Ethylglyoxal Bis(Guanylhydrazone) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.