Description

1-Chloro-2,3,5,6-Tetrafluorobenzene is a versatile fluorinated aromatic building block, valued for its unique combination of halogen substituents which impart significant chemical stability and reactivity. This compound is essential for synthesizing advanced materials and active pharmaceutical ingredients where precise fluorination patterns are required. It is primarily sought by R&D laboratories and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A key synthon for the development of fluorinated drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving performance and durability.
• Polymer Modification: Employed to introduce fluorine into polymer backbones, enhancing properties like chemical resistance and thermal stability.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to create complex, multi-substituted aromatic systems.
• Refrigerant & Propellant Research: Investigated as a potential component or intermediate in next-generation fluorocarbon blends.

Basic Information

Product Name	1-Chloro-2,3,5,6-Tetrafluorobenzene
CAS No.	1835-61-6
Molecular Formula	C6HClF4
Molecular Weight	184.52 g/mol
Synonyms	2,3,5,6-Tetrafluoro-1-chlorobenzene; 1-Chloro-2,3,5,6-tetrafluorobenzene; Benzene, 1-chloro-2,3,5,6-tetrafluoro-; p-Chlorotetrafluorobenzene; NSC 9235; 2,3,5,6-Tetrafluorochlorobenzene; Chlorotetrafluorobenzene
EINECS	217-406-7

Quality Control

Our 1-Chloro-2,3,5,6-Tetrafluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is 2-25°C. The container should be kept upright and securely sealed to prevent moisture ingress and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (20°C)	~1.60 g/mL
Boiling Point	~142-144 °C
Refractive Index (n20D)	~1.445

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.