Description

2-Fluoro-Pyridin-3-Yl-Amine Hcl is a high-purity, halogenated pyridine derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the 3-amino-2-fluoropyridine scaffold, a key pharmacophore in medicinal chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its fluorinated pyridine structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its aromatic amine functionality.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags, molecular probes, and other tools for biochemical research.

Basic Information

Product Name	2-Fluoro-Pyridin-3-Yl-Amine Hcl
CAS No.	1827-26-5
Molecular Formula	C5H6FN2•HCl
Molecular Weight	148.57 g/mol (Free base); 185.02 g/mol (HCl salt)
Synonyms	3-Amino-2-fluoropyridine hydrochloride; 2-Fluoro-3-pyridinamine hydrochloride; 2-Fluoropyridin-3-amine HCl; 2-Fluoro-3-aminopyridine hydrochloride; 3-Amino-2-fluoro-pyridine HCl; 2-Fluoro-3-pyridylamine hydrochloride; 2-F-3-APy•HCl
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-Pyridin-3-Yl-Amine Hcl is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.