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1-(2-Bromo-1-Fluoroethyl)Benzene CAS NO 1786-36-3
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CAS No.:1786-36-3
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
1-(2-Bromo-1-Fluoroethyl)Benzene is a valuable halogenated aromatic building block, specifically a benzyl halide derivative, with the CAS registry number 1786-36-3. This compound is engineered to serve as a key intermediate in advanced organic synthesis, offering a reactive handle for introducing both fluorine and bromine functionalities into target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated and brominated ethylbenzene motifs.
- Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
- Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic electronic materials, contributing to improved performance in display and lighting technologies.
- Cross-Coupling Reactions: The bromine atom makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Kumada couplings to form new carbon-carbon bonds.
- Fluorine Chemistry Exploration: Utilized in methodological studies to investigate the unique reactivity of vicinal bromo-fluoro compounds.
- Polymer Modification: Acts as a functional monomer or grafting agent to introduce halogenated phenyl groups into polymer backbones, altering material properties.
Basic Information
| Product Name | 1-(2-Bromo-1-Fluoroethyl)Benzene |
| CAS No. | 1786-36-3 |
| Molecular Formula | C8H8BrF |
| Molecular Weight | 203.05 g/mol |
| Synonyms | (2-Bromo-1-fluoroethyl)benzene; α-Fluoro-β-bromoethylbenzene; 2-Bromo-1-fluoro-1-phenylethane; 1-Bromo-2-fluoro-2-phenylethane; Benzene, (2-bromo-1-fluoroethyl)-; 2-Bromo-1-fluoroethylbenzene; 1-Fluoro-2-bromoethylbenzene; Phenethyl bromide, α-fluoro- |
| EINECS | Contact for details |
Quality Control
Our 1-(2-Bromo-1-Fluoroethyl)Benzene is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting key parameters such as assay and impurity profiles. Our commitment to consistent quality and traceability supports your R&D and scale-up processes with reliable material.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture ingress and decomposition.
Specification
| Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Identification (IR) | Conforms to structure |
| Purity (GC) | ≥ 97.0% |
| Water Content (KF) | ≤ 0.5% |
| Related Substances (GC) | Individual impurity ≤ 1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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