Description

α-Bromo-2,3,4,5,6-Pentafluorotoluene is a high-value, multi-fluorinated aromatic building block essential for advanced chemical synthesis. This compound is critical for introducing the pentafluorotoluene moiety into target molecules, enabling the fine-tuning of electronic and steric properties. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of fluorinated drug candidates, particularly for CNS and oncology targets, where fluorine substitution enhances metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and pesticides, where the pentafluorotoluene group contributes to improved lipophilicity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated components in electronic display materials, enhancing charge transport properties and thermal stability.
• Polymer Modification: Employed to create specialty fluorinated monomers for high-performance polymers with enhanced chemical resistance and low surface energy.
• Catalyst Ligand Synthesis: Utilized in the preparation of sophisticated fluorinated ligands for transition metal catalysis, enabling more selective and efficient reactions.
• Organic Synthesis Reagent: Functions as a versatile reagent for nucleophilic aromatic substitution (SNAr) reactions, facilitating the introduction of complex functionalities.

Basic Information

Product Name	α-Bromo-2,3,4,5,6-Pentafluorotoluene
CAS No.	1765-40-8
Molecular Formula	C7H2BrF5
Molecular Weight	260.99 g/mol
Synonyms	2-Bromo-1,3,4,5,6-pentafluorobenzene; Pentafluorobenzyl Bromide; α-Bromopentafluorotoluene; (Bromomethyl)pentafluorobenzene; Benzene, 1-bromo-2,3,4,5,6-pentafluoro-; 2,3,4,5,6-Pentafluorobenzyl Bromide; PFBBr; 1765-40-8
EINECS	217-189-8

Quality Control

Every batch of α-Bromo-2,3,4,5,6-Pentafluorotoluene is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15-25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.