Description

1,4-Difluoro-2,3-Dimethylbenzene is a versatile fluorinated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the strategic placement of fluorine atoms and methyl groups, which allows for precise tuning of electronic properties and steric bulk in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic cores to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of modern herbicides, fungicides, and insecticides, where the difluoro-dimethylbenzene structure contributes to efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, influencing dielectric anisotropy and molecular alignment.
• Polymer & Resin Modifier: Incorporated into specialty polymers to impart specific chemical resistance, thermal stability, or altered surface properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Negishi) and nucleophilic aromatic substitution reactions to construct complex molecular architectures.
• Research & Development: A valuable compound for academic and industrial R&D in medicinal chemistry and material science for exploring new chemical entities.

Basic Information

Product Name	1,4-Difluoro-2,3-Dimethylbenzene
CAS No.	1736-90-9
Molecular Formula	C8H8F2
Molecular Weight	142.15 g/mol
Synonyms	2,3-Dimethyl-1,4-difluorobenzene; 1,4-Difluoro-2,3-xylene; 2,3-Dimethyl-p-difluorobenzene; Benzene, 1,4-difluoro-2,3-dimethyl-; p-Difluoro-2,3-dimethylbenzene; 2,3-Dimethyl-1,4-difluorobenzol; NSC 406106
EINECS	217-085-9

Quality Control

Our 1,4-Difluoro-2,3-Dimethylbenzene is produced and handled under a strict quality management system. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-25°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.12 g/cm³
Boiling Point	~155-160 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.