Description

3-Chloro-2,4,5,6-Tetrafluoropyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique halogenated structure makes it an invaluable intermediate for introducing both fluorine and chlorine substituents into target molecules, enabling precise tuning of electronic and physical properties. This compound is essential for researchers and manufacturers in the agrochemical and pharmaceutical industries developing next-generation active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of novel herbicides, fungicides, and insecticides, where its fluorinated pyridine core contributes to enhanced biological activity and environmental stability.
• Pharmaceutical Building Block: Used in medicinal chemistry for the development of active pharmaceutical ingredients (APIs), particularly in creating molecules with improved metabolic stability and membrane permeability.
• Liquid Crystal & Electronic Materials: Serves as a starting material for synthesizing fluorinated liquid crystals and organic semiconductors used in display technologies and electronic devices.
• Specialty Polymer Modification: Employed to introduce fluorine and chlorine functionalities into polymer backbones, enhancing properties like chemical resistance, thermal stability, and low surface energy.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille) to construct complex, polyfunctionalized aromatic systems for various R&D applications.

Basic Information

Product Name	3-Chloro-2,4,5,6-Tetrafluoropyridine
CAS No.	1735-84-8
Molecular Formula	C5HClF4N
Molecular Weight	183.51 g/mol
Synonyms	2,4,5,6-Tetrafluoro-3-chloropyridine; 3-Chlorotetrafluoropyridine; Pyridine, 3-chloro-2,4,5,6-tetrafluoro-; NSC 406912; 3-Chloro-2,4,5,6-tetrafluoropyridine; Tetrafluoro-3-chloropyridine
EINECS	217-083-3

Quality Control

Every batch of 3-Chloro-2,4,5,6-Tetrafluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and high volatility, ensure containers are kept tightly sealed and away from heat, sparks, and open flame. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.