Description

4-Methylpiperazine-1-Sulfonyl Chloride is a versatile sulfonyl chloride derivative, a key reactive intermediate in organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the 4-methylpiperazine-1-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, especially in the development of kinase inhibitors, receptor antagonists, and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the sulfonamide group can enhance biological activity.
• Chemical Biology & Proteomics: Serves as a reagent for modifying proteins, peptides, and other biomolecules to study function or create bioconjugates.
• Material Science Research: Employed in the synthesis of functional polymers and advanced materials with specific sulfonamide linkages.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	4-Methylpiperazine-1-Sulfonyl Chloride
CAS No.	1688-95-5
Molecular Formula	C5H11ClN2O2S
Molecular Weight	198.67 g/mol
Synonyms	1-(4-Methylpiperazinyl)sulfonyl chloride; N-(4-Methylpiperazinyl)sulfonyl chloride; 4-Methyl-1-piperazinesulfonyl chloride; 4-Methylpiperazine-1-sulfonyl chloride; 1-Piperazinesulfonyl chloride, 4-methyl-; 4-Methylpiperazine sulfonyl chloride; 4-Methylpiperazinylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methylpiperazine-1-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical and research applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.