Description

4-Amino-2,3,5,6-Tetrafluoropyridine is a high-value, multi-fluorinated pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring an amino group on a perfluorinated pyridine ring, makes it an essential precursor for introducing fluorine atoms into complex molecules, thereby modifying their electronic properties, metabolic stability, and lipophilicity. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty materials sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in oncology, CNS, and antiviral research, where fluorine substitution is used to optimize potency and ADME properties.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging fluorine's ability to enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Used to prepare fluorinated ligands for transition metal catalysis, enabling new reaction pathways and improved selectivity in fine chemical production.
• Material Science Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials to impart desired thermal, optical, or surface properties.
• Fluorinated Dye and Pigment Chemistry: Serves as a starting material for creating specialized fluorophores and colorants with unique spectral characteristics.
• Custom Synthesis and Contract Research: A valuable reagent for custom synthesis houses and R&D laboratories focused on fluorine chemistry and scaffold diversification.

Basic Information

Product Name	4-Amino-2,3,5,6-Tetrafluoropyridine
CAS No.	1682-20-8
Molecular Formula	C5H2F4N2
Molecular Weight	166.08 g/mol
Synonyms	2,3,5,6-Tetrafluoro-4-pyridinamine; 4-Pyridinamine, 2,3,5,6-tetrafluoro-; 4-Aminotetrafluoropyridine; 2,3,5,6-Tetrafluoropyridin-4-amine; Tetrafluoro-4-aminopyridine; 4-Amino-2,3,5,6-tetrafluoropyridine; 1682-20-8; 4-Amino-perfluoropyridine
EINECS	Contact for details

Quality Control

Our 4-Amino-2,3,5,6-Tetrafluoropyridine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, NMR, and mass spectrometry, for comprehensive identity confirmation and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and specific test results. Our quality system supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong acids, strong bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.