Description

(3R)-2,3-Dihydro-6-Hydroxy-3-(Hydroxymethyl)-2-Methyl-10H-3α,10Aα-Epidithiopyrazino[1,2-A]Indole-1,4-Dione is a complex heterocyclic compound featuring a unique epidithiodiketopiperazine (ETP) core structure, which is of significant interest in synthetic organic chemistry and medicinal research. This compound matters as a key synthetic intermediate or reference standard for the development of novel bioactive molecules, particularly those targeting specific enzymatic pathways. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing new therapeutic agents or studying structure-activity relationships.

Application

• Pharmaceutical Research & Development: Serves as a critical synthetic intermediate or building block in the discovery and synthesis of novel drug candidates, especially those with potential anticancer or antimicrobial activity.
• Medicinal Chemistry Studies: Used as a reference standard or probe compound to investigate the biological activity and mechanism of action associated with the epidithiodiketopiperazine pharmacophore.
• Academic & Institutional Research: Employed in universities and research institutes for studying complex organic synthesis methodologies, heterocyclic chemistry, and natural product synthesis.
• Biochemical Tool Compound: Potential use as a biochemical tool to study cellular processes like apoptosis or specific protein-protein interactions in biological assays.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of more complex molecules for clients in the agrochemical or advanced material sectors.

Basic Information

Product Name	(3R)-2,3-Dihydro-6-Hydroxy-3-(Hydroxymethyl)-2-Methyl-10H-3α,10Aα-Epidithiopyrazino[1,2-A]Indole-1,4-Dione
CAS No.	1668-07-1
Molecular Formula	C₁₄H₁₂N₂O₄S₂
Molecular Weight	336.39 g/mol
Synonyms	6-Hydroxy-3-(hydroxymethyl)-2-methyl-2,3-dihydro-10H-3a,10a-epidithiopyrazino[1,2-a]indole-1,4-dione; (3R)-Epidithiodiketopiperazine derivative; Gliotoxin precursor analogue; 3a,10a-Epidithio-6-hydroxy-3-(hydroxymethyl)-2-methyl-2,3-dihydro-10H-pyrazino[1,2-a]indole-1,4-dione; (R)-6-Hydroxy-3-(hydroxymethyl)-2-methyl-2,3-dihydro-10H-[1,4]dithiino[2,3-b]indole-1,4-dione (fused ring system representation); ARA 001 (potential research code); Contact for additional trade/abbreviated names.
EINECS	Contact for details

Quality Control

Our (3R)-2,3-Dihydro-6-Hydroxy-3-(Hydroxymethyl)-2-Methyl-10H-3α,10Aα-Epidithiopyrazino[1,2-A]Indole-1,4-Dione is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, MS, IR), to ensure it meets precise customer specifications and research-grade standards. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to ensure full traceability and support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term stability, especially after the original container has been opened. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Research Grade)
Purity (HPLC)	≥ 98.0% (Premium Grade)
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.