Description

3-Chloropropanesulfonyl Chloride is a versatile and highly reactive bifunctional organosulfur compound, serving as a critical building block in advanced organic synthesis. Its dual functionality enables the efficient introduction of both chloropropyl and sulfonyl chloride groups, making it indispensable for constructing complex molecular architectures. This intermediate is primarily sought after by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based drugs, including protease inhibitors and kinase inhibitors.
• Agrochemical Synthesis: Used in manufacturing herbicides, fungicides, and plant growth regulators that incorporate sulfonyl moieties.
• Polymer Modification: Acts as a reactive site for introducing sulfonyl chloride groups into polymers for ion-exchange resins or functional materials.
• Chemical Biology & Proteomics: Useful as a labeling or cross-linking reagent for modifying proteins and other biomolecules.
• Dye & Pigment Manufacturing: Intermediate in the production of sulfonated dyes and optical brighteners.
• Ligand & Catalyst Development: Building block for creating novel sulfonated ligands used in catalytic systems.

Basic Information

Product Name	3-Chloropropanesulfonyl Chloride
CAS No.	1633-82-5
Molecular Formula	C3H6Cl2O2S
Molecular Weight	193.05 g/mol
Synonyms	3-Chloro-1-propanesulfonyl chloride; 3-Chloropropane-1-sulfonyl chloride; γ-Chloropropanesulfonyl chloride; 1-Chloro-3-(chlorosulfonyl)propane; NSC 401124; 3-Chloropropylsulfonyl chloride; Propane, 1-chloro-3-(chlorosulfonyl)-
EINECS	216-656-8

Quality Control

Every batch of 3-Chloropropanesulfonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the precise requirements for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and reacts with water; ensure containers are kept tightly sealed in a dry environment. Keep away from strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 1.0% (total)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.