Description

Chloroacetic-2-13C Acid is a stable isotope-labeled derivative of chloroacetic acid, where the carbon-2 position is enriched with the 13C isotope. This precise labeling is critical for advanced analytical and research applications, providing a non-radioactive tracer for mechanistic studies and metabolic pathway analysis. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require high-fidelity isotopic compounds for mass spectrometry, NMR spectroscopy, and the synthesis of labeled active pharmaceutical ingredients (APIs).

Application

• Metabolic Pathway Tracing: Used as a 13C-labeled precursor in biochemical research to track metabolic fluxes and elucidate biosynthetic pathways.
• Pharmaceutical Research & Development: A key intermediate in the synthesis of carbon-13 labeled active pharmaceutical ingredients (APIs) for drug metabolism and pharmacokinetics (DMPK) studies.
• Analytical Chemistry Standards: Serves as an internal standard or reference material in quantitative mass spectrometry (LC-MS, GC-MS) for accurate quantification of chloroacetic acid and related compounds.
• Agrochemical Studies: Employed in environmental fate and metabolism studies of herbicides and plant growth regulators derived from chloroacetic acid.
• NMR Spectroscopy: Provides a distinct 13C NMR signal for structural analysis and reaction monitoring in synthetic organic chemistry.
• Chemical Synthesis: Acts as a labeled synthon for introducing the 13C isotope into more complex organic molecules for various research purposes.

Basic Information

Product Name	Chloroacetic-2-13C Acid
CAS No.	1633-47-2
Molecular Formula	C13CH2ClCOOH
Molecular Weight	95.49 g/mol (for 13C1 isotopologue)
Synonyms	2-Chloroacetic-2-13C Acid; Monochloroacetic-2-13C Acid; Chloroethanoic-2-13C Acid; MCA-2-13C; (2-13C)Chloroacetic Acid; 13C-Labeled Chloroacetic Acid; 2-Chloro[2-13C]acetic Acid; [2-13C]-Chloroacetic Acid
EINECS	Contact for details

Quality Control

Our Chloroacetic-2-13C Acid is manufactured under controlled conditions to ensure exceptional isotopic and chemical purity. Each batch undergoes rigorous analysis, including NMR and mass spectrometry, to confirm isotopic enrichment and chemical identity. A comprehensive Certificate of Analysis (COA) detailing isotopic purity (atom% 13C), chemical purity (by HPLC/GC), and other critical parameters is provided with every shipment to support your research integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and a strong acid/organic solvent. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Isotopic Purity (atom% 13C)	≥ 99%
Chemical Purity (HPLC)	≥ 98%
Isotopic Enrichment (MS)	≥ 99% at C-2 position
Melting Point	60 - 63 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.