Description

Chloroacetic Acid-1-14C 20-40 Mci Permmo L is a high-specific-activity, carbon-14 radiolabeled derivative of chloroacetic acid, a key chemical intermediate. This product is essential for conducting precise metabolic and environmental fate studies, providing critical data for regulatory submissions and advanced research. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and environmental science researchers who require reliable, high-purity radiotracers for autoradiography, ADME (Absorption, Distribution, Metabolism, Excretion) studies, and degradation pathway analysis.

Application

• Pharmaceutical Metabolism Studies: As a radiolabeled tracer in ADME studies to track the metabolic pathways of drug candidates and their metabolites.
• Agrochemical Research: For investigating the environmental fate, degradation, and soil metabolism of herbicides and pesticides derived from chloroacetic acid.
• Biochemical Pathway Analysis: Used in enzymatic studies and biochemical research to elucidate specific reaction mechanisms involving acetyl groups.
• Environmental Science: Tracing the breakdown and persistence of chloroacetate compounds in various ecosystems and water treatment processes.
• Chemical Synthesis Intermediary: Serving as a labeled building block for the synthesis of more complex carbon-14 labeled compounds for research purposes.

Basic Information

Item	Detail
Product Name	Chloroacetic Acid-1-14C 20-40 Mci Permmo L
CAS No.	1633-46-1
Molecular Formula	C14CH2ClCOOH / C2H3ClO2 (¹⁴C labeled)
Molecular Weight	~94.50 g/mol (unlabeled)
Synonyms	Monochloroacetic Acid-1-¹⁴C; Chloroethanoic Acid-1-¹⁴C; 2-Chloroacetic Acid-1-¹⁴C; MCA-1-¹⁴C; [1-¹⁴C]Chloroacetic Acid; Carboxy-¹⁴C-chloroacetic Acid; α-Chloroacetic Acid-1-¹⁴C; Chloroacetic-1-¹⁴C Acid
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled Chloroacetic Acid-1-14C is manufactured and tested under strict quality systems to ensure high chemical and radiochemical purity, specific activity, and stability. Production adheres to cGMP principles where applicable for research materials. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for assay, radiochemical purity, specific activity, and solvent composition.

Storage

Preserve in a tightly closed container, protected from light. Store at or below -20°C in a dedicated, appropriately shielded freezer. The product is a strong acid/organic solvent and should be handled with appropriate radiological and chemical safety precautions in a well-ventilated area.

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Identification (IR/HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98% (chemical purity)
Radiochemical Purity (HPLC)	≥ 97%
Specific Activity	20 - 40 mCi/mmol
Solvent	Specified inert solvent (e.g., Toluene, Benzene)
Concentration	1.0 mCi/mL (typical)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.