Description

4-Methyl-2-(Trifluoromethyl)Pyridine is a versatile fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique combination of the electron-deficient pyridine ring and the robust trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to final compounds. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides and herbicides, where the trifluoromethyl group often contributes to improved biological activity and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in fine chemical and petrochemical processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials that require fluorinated aromatic components.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in laboratory and production settings.

Basic Information

Product Name	4-Methyl-2-(Trifluoromethyl)Pyridine
CAS No.	1620-79-7
Molecular Formula	C7H6F3N
Molecular Weight	161.12 g/mol
Synonyms	2-(Trifluoromethyl)-4-picoline; 4-Methyl-2-(trifluoromethyl)pyridine; 2-Trifluoromethyl-4-methylpyridine; α,α,α-Trifluoro-4-picoline; 4-Methyl-α,α,α-trifluoro-2-pyridinemethane; 4-Methyl-2-trifluoromethylpyridine; 2-Pyridinemethanol, α,α,α-trifluoro-4-methyl-
EINECS	Contact for details

Quality Control

Our 4-Methyl-2-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure it meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.