Description

Galanthamine, 10-Demethyl-, Compd. With (3.Alpha.,4A.Beta.,4B.Beta.)-10-Demethyl-1,2-Dihydrogalanthamine (1:1) is a high-purity alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate and reference standard in the synthesis and study of acetylcholinesterase inhibitors. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel therapeutic agents for neurological conditions.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthetic pathways for advanced galanthamine analogs and related therapeutic compounds.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and research laboratories for method development and validation.
• Biochemical Research: Employed in in vitro studies to investigate mechanisms of acetylcholinesterase inhibition and structure-activity relationships (SAR).
• Active Pharmaceutical Ingredient (API) Development: A key starting material for the research-scale synthesis of potential new chemical entities (NCEs) targeting cognitive disorders.
• Academic Research: Utilized in university and institutional labs for pharmacological and phytochemical studies related to Amaryllidaceae alkaloids.

Basic Information

Product Name	Galanthamine, 10-Demethyl-, Compd. With (3.Alpha.,4A.Beta.,4B.Beta.)-10-Demethyl-1,2-Dihydrogalanthamine (1:1)
CAS No.	1359-83-7
Molecular Formula	C17H21NO3 • C17H23NO3
Molecular Weight	659.77 g/mol (for the 1:1 compound)
Synonyms	10-Demethylgalanthamine compound with 10-demethyl-1,2-dihydrogalanthamine (1:1); 10-Demethylgalanthamine - 10-Demethyldihydrogalanthamine (1:1); Galanthamine, 10-demethyl-, compd. with 10-demethyl-1,2-dihydrogalanthamine (1:1); Lycoramine, 10-demethyl-, compd. with 10-demethyl-1,2-dihydrolycoramine (1:1); (3α,4aβ,4bβ)-10-Demethyl-1,2-dihydrogalanthamine compound with 10-demethylgalanthamine; Amaryllidaceae alkaloid derivative.
EINECS	Contact for details

Quality Control

Our Galanthamine derivative is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. All materials undergo comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR). A detailed Certificate of Analysis (COA) is provided with each shipment, documenting key specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.