Description

4',5'-Didehydro-4'-Deoxy-2',19'-Dioxo-2',19'-Secovincaleukoblastine CAS NO 1355-31-3 is a complex, semi-synthetic derivative of the vinca alkaloid family, representing a key intermediate in advanced pharmaceutical research and development. This compound is of significant interest for its potential role in the synthesis of novel therapeutic agents targeting oncological and neurological pathways. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of next-generation alkaloid-based medicines.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel vinca alkaloid derivatives and analogs for preclinical and clinical research.
• Oncology Research: Used in the development and study of potential anti-mitotic and anti-cancer agents that target tubulin polymerization.
• Neurological Agent Development: Serves as a precursor in research focused on creating new compounds for investigating neurological disorders and pathways.
• Medicinal Chemistry Studies: Employed as a reference standard or a starting material for structure-activity relationship (SAR) studies to optimize biological activity and reduce toxicity.
• Process Chemistry & Scale-Up: Utilized in the development and optimization of synthetic routes for the production of complex natural product derivatives at pilot and commercial scales.
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies in organic synthesis, chemical biology, and pharmacology.

Basic Information

Product Name	4',5'-Didehydro-4'-Deoxy-2',19'-Dioxo-2',19'-Secovincaleukoblastine
CAS No.	1355-31-3
Molecular Formula	C46H56N4O8
Molecular Weight	792.97 g/mol
Synonyms	4',5'-Didehydro-4'-deoxy-2',19'-dioxo-2',19'-secovincaleukoblastine; 2',19'-Secovincaleukoblastine-2',19'-dione, 4',5'-didehydro-4'-deoxy-; 4'-Deoxy-4',5'-didehydro-2',19'-dioxo-2',19'-secovincaleukoblastine; Vinblastine derivative; Secovincaleukoblastine dione derivative; 1355-31-3; 4',5'-Didehydro-4'-deoxyvinblastine-2',19'-dione
EINECS	Contact for details

Quality Control

Our 4',5'-Didehydro-4'-Deoxy-2',19'-Dioxo-2',19'-Secovincaleukoblastine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Single Maximum Unknown Impurity	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.