Description

(20S)-3α-(Dimethylamino)-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone is a high-purity steroidal alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate and reference standard for the production and analysis of complex bioactive molecules. It is primarily utilized by research institutions, pharmaceutical companies, and fine chemical manufacturers engaged in steroid chemistry, oncology research, and the development of novel therapeutic agents. Our supply ensures consistent quality and reliable availability for your most demanding projects.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control of related compounds.
• Biochemical Research: Employed in academic and industrial research to study steroid receptor interactions, metabolic pathways, and structure-activity relationships (SAR).
• Process Development: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for target molecules in preclinical and clinical development.

Basic Information

Product Name	(20S)-3α-(Dimethylamino)-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone
CAS No.	1244-02-6
Molecular Formula	C24H37NO3
Molecular Weight	387.56 g/mol
Synonyms	3α-(Dimethylamino)-20-hydroxypregn-5-en-18-oic acid γ-lactone; 20S-Veratramine γ-Lactone; Veratramine Lactone; (20S)-3α-(Dimethylamino)-20-hydroxy-5-pregnen-18-oic acid γ-lactone; NSC 529079; Pregn-5-en-18-oic acid, 3-(dimethylamino)-20-hydroxy-, γ-lactone, (3α,20S)-
EINECS	Contact for details

Quality Control

Our (20S)-3α-(Dimethylamino)-20-Hydroxypregn-5-En-18-Oic Acid γ-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.