Description

3,12-Dioxo-5α-Cholan-24-Oic Acid Methyl Ester is a high-purity steroidal intermediate of significant importance in advanced organic synthesis. This compound matters as a key building block for the preparation of more complex bile acid derivatives and pharmaceutical actives. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing novel therapeutic agents and reference standards.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial R&D for studying bile acid metabolism and developing new chemical entities.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of specialized cholanic acid derivatives for various applications.
• Biochemical Research: Utilized in studies related to nuclear receptor binding and metabolic pathway investigations.

Basic Information

Product Name	3,12-Dioxo-5α-Cholan-24-Oic Acid Methyl Ester
CAS No.	1174-86-3
Molecular Formula	C₂₅H₃₈O₄
Molecular Weight	402.57 g/mol
Synonyms	Methyl 3,12-dioxo-5β-cholan-24-oate; Methyl 3,12-dioxocholanate; 3,12-Diketolithocholic Acid Methyl Ester; Methyl 3,12-dioxo-5β-cholan-24-oate; 5β-Cholan-24-oic acid, 3,12-dioxo-, methyl ester; Methyl 3,12-dioxolithocholate
EINECS	Contact for details

Quality Control

Our 3,12-Dioxo-5α-Cholan-24-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-grade specifications. Certificates of Analysis (COA) detailing all test results are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. This product is light-sensitive and should be stored away from light as indicated.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.