Description

2-Bromobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its core value lies in the synergistic reactivity of the bromine substituent and the electron-withdrawing trifluoromethyl group, enabling precise molecular construction. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries who require high-purity intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) via cross-coupling reactions like Suzuki, Negishi, or Buchwald-Hartwig amination.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated aromatic cores in electronic and display materials.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or N-heterocyclic carbene (NHC) ligands for catalysis.
• Polymer Modification: Incorporated into polymer backbones to impart unique solubility, thermal stability, or surface properties.
• Organic Synthesis Research: A fundamental reagent for exploring new C-C and C-X bond-forming methodologies in academic and industrial R&D settings.

Basic Information

Product Name	2-Bromobenzotrifluoride
CAS No.	392-83-6
Molecular Formula	C7H4BrF3
Molecular Weight	225.01 g/mol
Synonyms	α,α,α-Trifluoro-o-bromotoluene; 2-Bromo-α,α,α-trifluorotoluene; o-Bromobenzotrifluoride; 1-Bromo-2-(trifluoromethyl)benzene; 2-Bromo-α,α,α-trifluorotoluene; 2-Bromobenzylidene trifluoride; (2-Bromophenyl)trifluoromethane; Benzene, 1-bromo-2-(trifluoromethyl)-
EINECS	206-876-5

Quality Control

Our 2-Bromobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	1.60 - 1.65 g/mL
Refractive Index (n20D)	1.470 - 1.480

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.