Quinolones

Synthetic Anti-Infective Drugs

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Quinolones

Quinolones are synthetic broad-spectrum antibacterial agents that exert their activity by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. These drugs, including ciprofloxacin, levofloxacin, moxifloxacin, and ofloxacin, demonstrate potent bactericidal effects against Gram-negative organisms and enhanced activity against Gram-positive pathogens in newer generations. Their excellent tissue penetration and oral bioavailability make them widely used for respiratory infections, urinary tract infections, gastrointestinal infections, bone and joint infections, and certain cases of sepsis. However, concerns such as tendinopathy, QT prolongation, CNS effects, and emerging resistance require careful prescribing. Despite these limitations, quinolones remain cornerstone therapeutics in many clinical settings due to their broad spectrum, rapid onset, and versatile dosing options.

7H-Pyrido[1,2,3-De]-1,4-Benzoxazine-6-Carboxylic Acid, 9-Fluoro-2,3-Dihydro-2-Methyl-10-(4-Methyl-1-Piperazinyl)-7-Oxo-, (S)- (9Ci) CAS NO 129815-82-3

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CAS No.:129815-82-3

Grade:Pharmacy Grade

Content:99.90%

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3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-(4-Ethyl-1-Piperazinyl)-6,8-Difluoro-1,4-Dihydro-4-Oxo- CAS NO 131776-00-6

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CAS No.:131776-00-6

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Content:99.90%

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7-[(3S)-3-Aminopyrrolidin-1-Yl]-1-Cyclopropyl-6,8-Difluoro-4-Oxo-Quino Line-3-Carboxylic Acid CAS NO 133298-78-9

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CAS No.:133298-78-9

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Content:99.90%

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3-Quinolinecarboxylic Acid, 1-Cyclopropyl-7-[2-[(Dimethylamino)Methyl]-4-Morpholinyl]-6-Fluoro-1,4-Dihydro-8-Methoxy-4-Oxo- CAS NO 133762-22-8

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CAS No.:133762-22-8

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Content:99.90%

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(3S )-8-Amino-9,10-Difluoro-2,3-Dihydro-3-Methyl-7-Oxo-7H -Pyrido[1,2,3-De ]-1,4-Benzoxazine-6-Carboxylic Acid CAS NO 135325-15-4

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CAS No.:135325-15-4

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Content:99.90%

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Pazufloxacin Mesylate CAS NO 136905-87-8

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CAS No.:136905-87-8

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Content:99.90%

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1-Cyclopropyl-6-Fluoro-1,4-Dihydro-4-Oxo-1,8-Naphthyridine-3-Carboxylic Acid CAS NO 137118-01-5

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CAS No.:137118-01-5

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Content:99.90%

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Levofloxacin Hemihydrate CAS NO 138199-71-0

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CAS No.:138199-71-0

Grade:Pharmacy Grade

Content:99.90%

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