Description

1-Ethyl-8-Difluoromethoxy-6-Fluoro-1,4-Didehydro-7-[4-(2-Methoxyphenyl)-1-Piperazinyl]-4-Oxoquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the fluoroquinolone class of compounds. This compound is critical for the research and development of novel antibacterial agents, offering a sophisticated structural framework for medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in antimicrobial drug discovery and synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of next-generation fluoroquinolone antibiotics.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new antibacterial compounds with improved efficacy and reduced resistance.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating the mechanism of action of topoisomerase inhibitors.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing of specialized active pharmaceutical ingredients (APIs).
• Academic Research: A valuable compound for university and institutional research projects in organic chemistry and pharmacology.

Basic Information

Product Name	1-Ethyl-8-Difluoromethoxy-6-Fluoro-1,4-Didehydro-7-[4-(2-Methoxyphenyl)-1-Piperazinyl]-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	153468-00-9
Molecular Formula	C24H24F3N3O5
Molecular Weight	491.46 g/mol
Synonyms	Gatifloxacin Impurity; Gatifloxacin Related Compound; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid derivative; 8-Difluoromethoxy Gatifloxacin Intermediate; 7-[4-(2-Methoxyphenyl)-1-piperazinyl]-1-ethyl-6-fluoro-1,4-dihydro-8-(difluoromethoxy)-4-oxo-3-quinolinecarboxylic Acid; Tequin Impurity; AM-1155 Intermediate; Zymar Intermediate
EINECS	Contact for details

Quality Control

Our 1-Ethyl-8-Difluoromethoxy-6-Fluoro-1,4-Didehydro-7-[4-(2-Methoxyphenyl)-1-Piperazinyl]-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.