Description

Alatrofloxacin is a broad-spectrum fluoroquinolone antibiotic, specifically the L-alanyl prodrug of trovafloxacin, designed to enhance water solubility for parenteral administration. This compound is of significant interest in pharmaceutical research and development for its potent activity against a wide range of Gram-positive and Gram-negative bacteria. It is primarily utilized by pharmaceutical manufacturers and research institutions engaged in the development of advanced antibacterial therapies and the study of prodrug mechanisms.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of the active antibiotic, trovafloxacin.
• Antibacterial Research: Used in microbiological and pharmacological studies to investigate the efficacy and mechanisms of advanced fluoroquinolones.
• Prodrug Development: Acts as a model compound in research focused on enhancing the bioavailability and delivery of poorly soluble drug substances.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Clinical Trial Material: Supplied for use in non-clinical and clinical research studies evaluating new antibacterial formulations.

Basic Information

Product Name	Alatrofloxacin
CAS No.	157605-25-9
Molecular Formula	C₂₆H₂₅F₃N₅O₇
Molecular Weight	576.50 g/mol
Synonyms	Trovafloxacin L-alaninate; CP-116,517; Alatrofloxacin mesylate; (1α,5α,6α)-7-(6-Amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid L-alaninate; Trovafloxacin alaninyl ester; L-Alanine, ester with 7-(6-amino-3-azabicyclo[3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Alatrofloxacin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.