Description

1-Cyclopropyl-7-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct quinoline carboxylic acid structure. This compound is a critical building block in the synthesis of modern fluoroquinolone antibiotics, valued for its role in creating potent antimicrobial agents. It is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies focused on developing new antibacterial therapies.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of novel fluoroquinolone antibiotic APIs (Active Pharmaceutical Ingredients).
• Antibacterial Drug Research: Serves as a core scaffold in medicinal chemistry for designing and testing new antibacterial compounds with improved efficacy.
• Fine Chemical Synthesis: Used in multi-step organic synthesis for constructing complex heterocyclic molecules in pilot and commercial-scale processes.
• Biochemical Research: Employed in studies investigating the structure-activity relationships (SAR) of topoisomerase inhibitors.
• GMP Manufacturing: Supplied as a qualified starting material for cGMP (Current Good Manufacturing Practice) production of antibiotic drugs.

Basic Information

Product Name	1-Cyclopropyl-7-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
CAS No.	157372-99-1
Molecular Formula	C₁₃H₁₀FNO₃
Molecular Weight	247.22 g/mol
Synonyms	7-Fluoro-1-cyclopropyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 1-Cyclopropyl-7-fluoro-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid; 7-Fluoro-1-cyclopropyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-7-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 157372-99-1; Quinoline-3-carboxylic acid, 1-cyclopropyl-1,4-dihydro-7-fluoro-4-oxo-
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-7-Fluoro-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets stringent specifications for pharmaceutical intermediates. Certificates of Analysis (COA) are provided with every shipment, detailing identity, assay, and impurity profiles to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.