Description

(1R,1'R)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]-bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl]-isoquinolinium dibenzenesulfonate is a high-purity, complex bis-isoquinolinium salt derivative designed for advanced research and development applications. This compound is valued for its specific stereochemistry and structural features, making it a critical intermediate or reference standard in specialized chemical synthesis. It is primarily utilized by pharmaceutical R&D teams and academic research institutions focused on medicinal chemistry and neuropharmacology.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential therapeutic agents, particularly those targeting neurological pathways.
• Biochemical Research: Used as a reference standard or probe in studies investigating ion channel modulation or receptor-ligand interactions due to its bis-cationic structure.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop novel compounds with enhanced selectivity and potency.
• Process Development: Acts as a critical material for scaling up synthetic routes in pilot plant and pre-clinical manufacturing stages.
• Analytical Standard: Provides a high-purity benchmark for method development and validation in quality control laboratories using HPLC or LC-MS.

Basic Information

Item	Details
Product Name	(1R,1'R)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]-bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl]-isoquinolinium dibenzenesulfonate
CAS No.	96946-44-0
Molecular Formula	C68H82N2O18S2
Molecular Weight	1271.51 g/mol
Synonyms	Pentamethonium derivative; Bis-isoquinolinium salt; 1,1'-[Pentane-1,5-diylbis(oxy-3-oxopropane-3,1-diyl)]bis[2-methyl-6,7-dimethoxy-1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydroisoquinolinium] dibenzenesulfonate; (1R,1'R)-Bis-tetrahydroisoquinolinium salt; Galleinium salt analog; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our (1R,1'R)-2,2'-[1,5-pentanediylbis[oxy(3-oxo-3,1-propanediyl)]]-bis[1-[(3,4-dimethoxyphenyl)methyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl]-isoquinolinium dibenzenesulfonate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.