Description

(S)-Methocarbamol is the single enantiomer form of the centrally acting muscle relaxant methocarbamol. This high-purity chiral intermediate is critical for the development and manufacturing of enantiomerically pure pharmaceutical products, where the specific stereochemistry can significantly influence biological activity and safety profiles. It is primarily required by advanced pharmaceutical R&D laboratories and API manufacturers focused on producing next-generation musculoskeletal therapeutics with improved efficacy and reduced side-effect profiles.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of enantiopure muscle relaxant APIs.
• Analytical Reference Standard: Used in method development and quality control for chiral separation and assay testing.
• Preclinical & Clinical Research: Employed in pharmacological studies to investigate the stereospecific effects of methocarbamol.
• Process Chemistry Development: Serves as a critical material for developing and scaling up asymmetric synthesis routes.
• Impurity Standard: Used to identify and quantify the (S)-enantiomer as a potential impurity in racemic methocarbamol batches.

Basic Information

Product Name	(S)-Methocarbamol
CAS No.	108914-10-9
Molecular Formula	C11H15NO5
Molecular Weight	241.24 g/mol
Synonyms	(S)-3-(2-Methoxyphenoxy)-1,2-propanediol 1-carbamate; (S)-Guaiacol glycerol ether carbamate; (-)-Methocarbamol; Levomethocarbamol; (S)-Robaxin; L-Methocarbamol; (S)-2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate
EINECS	Contact for details

Quality Control

Our (S)-Methocarbamol is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity by HPLC, to ensure it meets the stringent requirements for pharmaceutical development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, enantiomeric excess, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.