Description

Mivacurium Chloride is a non-depolarizing neuromuscular blocking agent of the benzylisoquinolinium class, primarily used as a short-acting muscle relaxant in surgical anesthesia. Its rapid onset and short duration of action provide anesthesiologists with precise control during surgical procedures, facilitating optimal intubation and surgical conditions. This compound is essential for pharmaceutical manufacturers, research institutions, and contract development organizations (CDOs) involved in developing and producing anesthetic formulations and conducting pharmacological studies.

Application

• As an active pharmaceutical ingredient (API) in the formulation of injectable neuromuscular blocking agents for general anesthesia.
• Used in clinical and hospital settings to induce muscle paralysis during surgical procedures, including endotracheal intubation.
• Critical component in pharmacological research for studying neuromuscular junction physiology and the effects of muscle relaxants.
• Utilized in the development of generic and novel anesthetic drug products by pharmaceutical companies.
• Reference standard in analytical laboratories for quality control and method development using techniques like HPLC.
• Applied in preclinical animal studies to evaluate the efficacy and safety profiles of new anesthetic agents.

Basic Information

Product Name	Mivacurium Chloride
CAS No.	106861-44-3
Molecular Formula	C58H80N2O14 · 2Cl
Molecular Weight	1100.1 g/mol (for the dichloride salt)
Synonyms	Mivacurium Dichloride; BW B1090U; (1R,1'R,2S,2'S)-2,2'-(3,11-Dioxo-4,10-dioxatridecamethylene)bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium) Dichloride; MiVacron; 2,2'-[1,8-Dioxo-4,12-dioxa-1,8-diazatetradecanediyl]bis[1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-(3,4,5-trimethoxybenzyl)isoquinolinium] Dichloride
EINECS	Contact for details

Quality Control

Our Mivacurium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, potency, and safety, meeting stringent standards for pharmaceutical active ingredients. Certificates of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological limits are provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Microbiological Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.