Description

Pancuronium Bromide CAS NO 15500-66-0 is a non-depolarizing neuromuscular blocking agent belonging to the aminosteroid class. This compound is critically important as a skeletal muscle relaxant, primarily used to induce paralysis during surgical procedures and mechanical ventilation. It is an essential pharmaceutical active ingredient for manufacturers of injectable anesthetic and critical care formulations. The product's consistent quality and reliable pharmacological profile make it indispensable for ensuring controlled muscle relaxation in clinical settings.

Application

• Pharmaceutical Active Ingredient (API): Primary use as the key component in the manufacture of injectable neuromuscular blocking agents for anesthesia.
• Surgical Anesthesia: Used to provide skeletal muscle relaxation during a wide range of surgical procedures, facilitating optimal operating conditions.
• Intensive Care Unit (ICU) Management: Employed to facilitate endotracheal intubation and control ventilation in critically ill patients requiring mechanical respiratory support.
• Veterinary Medicine: Application in veterinary surgery for large animals where controlled muscle paralysis is required.
• Research & Development: Serves as a reference standard and tool compound in pharmacological research studying neuromuscular junction physiology and drug interactions.
• Generic Drug Formulation: Used by generic pharmaceutical companies in the development and production of cost-effective alternatives to branded neuromuscular blockers.

Basic Information

Item	Details
Product Name	Pancuronium Bromide
CAS No.	15500-66-0
Molecular Formula	C35H60Br2N2O4
Molecular Weight	732.69 g/mol
Synonyms	Pancuronium Dibromide; 2β,16β-Dipiperidino-5α-androstane-3α,17β-diol diacetate dimethobromide; Pavulon (Trade Name); NA 97; Mioblock; 1,1'-[3α,17β-Bis(acetyloxy)-5α-androstane-2β,16β-diyl]bis[1-methylpiperidinium] dibromide; (2β,3α,5α,16β,17β)-2,16-Bis(1-methyl-1-piperidiniumyl)-3,17-bis(acetyloxy)androstane dibromide
EINECS	239-553-1

Quality Control

Our Pancuronium Bromide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. We can supply material compliant with major pharmacopoeial standards, and a detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Microbial Limits	Meets requirements for non-sterile substance

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.