Description

Alcuronium Chloride CAS NO 15180-03-7 is a non-depolarizing neuromuscular blocking agent belonging to the class of bis-quaternary ammonium compounds. This pharmaceutical active ingredient is critical for inducing skeletal muscle relaxation during surgical procedures and mechanical ventilation. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of anesthetic formulations. The compound's specific pharmacological profile makes it a subject of ongoing research in neuromuscular physiology.

Application

• Primary use as a neuromuscular blocking agent in anesthetic formulations for surgical procedures.
• Key ingredient in the production of injectable pharmaceutical preparations for controlled muscle relaxation.
• Utilized in clinical research to study neuromuscular junction physiology and pharmacology.
• Reference standard in analytical laboratories for quality control and method development (HPLC, MS).
• Used in pharmacological studies investigating competitive antagonism at nicotinic acetylcholine receptors.
• Component in academic and institutional research exploring structure-activity relationships of muscle relaxants.

Basic Information

Product Name	Alcuronium Chloride
CAS No.	15180-03-7
Molecular Formula	C44H50Cl2N2O2
Molecular Weight	717.79 g/mol
Synonyms	Alloferin; Diallylnortoxiferine Dichloride; Alcuronium Dichloride; (1R,16R)-17,17-Diallyl-18,19-didehydro-10-methoxy-2,16-dimethyl-7,23-dioxa-2,16-diazaheptacyclo[17.7.1.112,15.03,8.08,27.013,28.020,25]octacosa-3,5,8(27),9,11,13(28),14,20,22,24,26-undecaene-4,29-diol Dichloride; Toxiferine Dichloride, Diallyl Derivative; Ro 4-3816
EINECS	Contact for details

Quality Control

Our Alcuronium Chloride is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing including identification, assay, and impurity profiling to ensure it meets stringent specifications suitable for pharmaceutical research and development. A Certificate of Analysis (COA) detailing results for purity (by HPLC), related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.