Description

N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamidedihydrochloride is a high-purity, complex heterocyclic compound designed for advanced research and development applications. This compound is of significant interest in pharmaceutical discovery due to its intricate molecular architecture, which combines pyrazolo-benzodiazepine and piperazine pharmacophores. It serves as a critical intermediate or reference standard for researchers in medicinal chemistry, process development, and analytical method validation targeting novel therapeutic agents.

Application

• Pharmaceutical Research & Development (R&D): Primary use as a key intermediate in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Medicinal Chemistry: Serves as a sophisticated building block for structure-activity relationship (SAR) studies and lead optimization programs.
• Process Chemistry: Used in the development and scale-up of synthetic routes for active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Provides a high-purity benchmark for quality control (QC) testing, method development, and regulatory submissions.
• Biochemical Screening: Acts as a test compound in high-throughput screening (HTS) assays to identify new biological targets and mechanisms of action.
• Academic Research: Utilized in university and institutional labs for cutting-edge studies in organic synthesis and pharmacology.

Basic Information

Product Name	N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamidedihydrochloride
CAS No.	847375-16-0
Molecular Formula	C33H36Cl2N6O4
Molecular Weight	651.59 g/mol
Synonyms	1-Piperazinecarboxamide, N-[[4-[(4,10-dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-, dihydrochloride; UNII-7K8J1O4F0H; 7K8J1O4F0H; 847375-16-0; N-({4-[(4,10-dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepine-5-carbonyl)-2-methylphenyl]methyl}-4-[(3,5-dihydroxyphenyl)methyl]piperazine-1-carboxamide dihydrochloride
EINECS	Contact for details

Quality Control

Our N-[[4-[(4,10-Dihydro-1-methylpyrazolo[3,4-b][1,5]benzodiazepin-5(1H)-yl)carbonyl]-2-methylphenyl]methyl]-4-[(3,5-dihydroxyphenyl)methyl]-1-piperazinecarboxamidedihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.