Description

5-(2-Fluorophenyl)-1,3-Dihydro-3-(1H-Indol-3-Ylmethyl)-1-Methyl-2H-1,4-Benzodiazepin-2-One is a high-purity, complex organic compound belonging to the benzodiazepine class, serving as a critical advanced intermediate in modern pharmaceutical research and development. Its intricate molecular structure makes it an essential building block for synthesizing novel therapeutic agents targeting the central nervous system. This compound is primarily sought after by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize biological activity and selectivity.
• Neurological Drug Discovery: Employed in the synthesis of potential therapeutic agents for disorders related to the GABAA receptor complex.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry Development: Utilized for scaling up and optimizing synthetic routes in pilot plants and kilo-labs.
• Academic Research: A valuable compound for universities and research institutes studying heterocyclic chemistry and neuropharmacology.

Basic Information

Product Name	5-(2-Fluorophenyl)-1,3-Dihydro-3-(1H-Indol-3-Ylmethyl)-1-Methyl-2H-1,4-Benzodiazepin-2-One
CAS No.	103342-82-1
Molecular Formula	C25H20FN3O
Molecular Weight	397.45 g/mol
Synonyms	3-[(1H-Indol-3-yl)methyl]-5-(2-fluorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(2-Fluorophenyl)-3-(indol-3-ylmethyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-3-(1H-indol-3-ylmethyl)-5-(2-fluorophenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Fluoro-benzodiazepine-indole derivative; CAS 103342-82-1
EINECS	Contact for details

Quality Control

Our 5-(2-Fluorophenyl)-1,3-Dihydro-3-(1H-Indol-3-Ylmethyl)-1-Methyl-2H-1,4-Benzodiazepin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.