Description

2H-1,4-Benzodiazepin-2-One, 7-Chloro-1,3-Dihydro-5-(4-Hydroxyphenyl)- CAS NO 17270-12-1 is a high-purity benzodiazepine derivative, a critical advanced pharmaceutical intermediate for the synthesis of active pharmaceutical ingredients (APIs). Its value lies in providing a reliable and consistent building block for complex drug molecules, ensuring downstream process integrity and final product quality. This compound is essential for research and development laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the production of specialized therapeutic agents.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial precursor in the multi-step synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Research & Development (R&D): Used in medicinal chemistry for the discovery and development of new therapeutic compounds targeting the central nervous system (CNS).
• Fine Chemical Manufacturing: Employed in the production of high-value, complex organic molecules for specialized applications.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Process Chemistry: Integral to scaling up synthetic routes from laboratory to pilot plant and commercial production scales.

Basic Information

Product Name	2H-1,4-Benzodiazepin-2-One, 7-Chloro-1,3-Dihydro-5-(4-Hydroxyphenyl)-
CAS No.	17270-12-1
Molecular Formula	C15H11ClN2O2
Molecular Weight	286.71 g/mol
Synonyms	7-Chloro-5-(4-hydroxyphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-(p-Hydroxyphenyl)-7-chloro-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 17270-12-1; 7-Chloro-5-(4'-hydroxyphenyl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Hydroxyphenzodiazepinone derivative; Benzodiazepine intermediate 17270-12-1
EINECS	Contact for details

Quality Control

Our 2H-1,4-Benzodiazepin-2-One, 7-Chloro-1,3-Dihydro-5-(4-Hydroxyphenyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We are committed to meeting the stringent requirements of pharmaceutical intermediate supply.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.