Description

Benzodiazepine CAS NO 1898-12-6 is a core heterocyclic compound belonging to the benzodiazepine class, which serves as a fundamental building block in medicinal chemistry. Its significance lies in its role as a key intermediate for the synthesis of various pharmacologically active agents, particularly central nervous system (CNS) drugs. This high-purity intermediate is essential for research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in creating new therapeutic molecules and generic APIs.

Application

• Pharmaceutical Intermediate: Primary use as a critical precursor in the synthesis of various benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a versatile scaffold for drug discovery programs targeting GABAA receptors and CNS disorders.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and impurity profiling.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct more complex molecular architectures with specific biological activity.

Basic Information

Item	Details
Product Name	Benzodiazepine
CAS No.	1898-12-6
Molecular Formula	C9H8N2
Molecular Weight	144.17 g/mol
Synonyms	1H-1,4-Benzodiazepine; 1,4-Benzodiazepine; Benzodiazepine base; 2,3-Dihydro-1H-1,4-benzodiazepine; NSC 51046; BZD core; 1,4-Benzodiazepine nucleus
EINECS	217-590-4

Quality Control

Our Benzodiazepine (CAS 1898-12-6) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A detailed Certificate of Analysis (COA) documenting purity, related substances, and residual solvents is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.