Description

7-Chloro-5-Cyclohexyl-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One is a high-purity benzodiazepine derivative, a critical building block in advanced pharmaceutical research and development. Its value lies in its role as a versatile synthetic intermediate for creating novel therapeutic agents targeting the central nervous system. This compound is essential for research chemists and pharmaceutical manufacturers focused on developing new anxiolytic, sedative, and anticonvulsant drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzodiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new compounds with targeted pharmacological profiles.
• Reference Standard: Serves as an analytical standard for quality control and method development in pharmaceutical laboratories.
• Preclinical Drug Development: Employed in the early-stage development of potential therapeutic agents for neurological and psychiatric disorders.
• Chemical Synthesis: Utilized in organic synthesis to construct complex heterocyclic frameworks for biological screening.

Basic Information

Item	Details
Product Name	7-Chloro-5-Cyclohexyl-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One
CAS No.	1784-78-7
Molecular Formula	C₁₆H₁₉ClN₂O
Molecular Weight	290.79 g/mol
Synonyms	7-Chloro-5-cyclohexyl-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 5-Cyclohexyl-7-chloro-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; 1-Methyl-7-chloro-5-cyclohexyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; U-31,889; U-31889; U31889; 1,4-Benzodiazepin-2-one, 7-chloro-5-cyclohexyl-1,3-dihydro-1-methyl-
EINECS	Contact for details

Quality Control

Every batch of our 7-Chloro-5-Cyclohexyl-1,3-Dihydro-1-Methyl-2H-1,4-Benzodiazepin-2-One is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for research and development applications. A detailed Certificate of Analysis (COA) with specifications for assay, related substances, and residual solvents is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.