Description

2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1H-1,4-Benzodiazepine Dimaleate is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API) of significant commercial and research interest. This compound is critical for ensuring the quality and efficacy of downstream pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and advanced research institutions engaged in the development and production of specialized therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex benzodiazepine-derived active pharmaceutical ingredients (APIs).
• Active Pharmaceutical Ingredient (API): Used as the core active component in the formulation of specific therapeutic drugs.
• Neurological & Psychiatric Research: Serves as a crucial reference standard and investigational compound in preclinical studies targeting central nervous system (CNS) disorders.
• Process Development & Scale-Up: Employed in R&D and pilot-scale manufacturing to optimize synthetic routes and ensure process robustness.
• Analytical Reference Standard: Used in quality control laboratories for method development, validation, and routine assay testing via HPLC, GC, or other chromatographic techniques.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of clinical trial materials or commercial drug products.

Basic Information

Product Name	2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1H-1,4-Benzodiazepine Dimaleate
CAS No.	59469-29-3
Molecular Formula	C26H23ClFN3O8
Molecular Weight	559.93 g/mol
Synonyms	7-Chloro-5-(2-fluorophenyl)-2-(aminomethyl)-2,3-dihydro-1H-1,4-benzodiazepine Dimaleate; 2-Aminomethyl-7-chloro-5-(2-fluorophenyl)-3H-1,4-benzodiazepine Dimaleate; Norfludiazepam Aminomethyl Derivative Dimaleate; Fludiazepam Related Compound; Benzodiazepine Derivative Dimaleate Salt; CAS 59469-29-3; Pharmaceutical Intermediate 59469-29-3
EINECS	Contact for details

Quality Control

Our 2-Aminomethyl-7-Chloro-2,3-Dihydro-5-(2-Fluorophenyl)-1H-1,4-Benzodiazepine Dimaleate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.