Description

3-Hydroxy-Prazepam is a key benzodiazepine metabolite and an important pharmaceutical reference standard. This compound is critical for analytical research, method development, and quality control in forensic and clinical toxicology. It is primarily utilized by research institutions, pharmaceutical manufacturers, and analytical laboratories for metabolite identification, pharmacokinetic studies, and ensuring the accuracy of diagnostic assays.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for the quantification of prazepam and its metabolites in drug testing and bioanalytical studies.
• Forensic Toxicology: Essential for the identification and confirmation of benzodiazepine use in forensic investigations and workplace drug testing.
• Clinical Research: Employed in pharmacokinetic and metabolic pathway studies to understand the disposition of prazepam in the human body.
• Method Development & Validation: Serves as a critical component in developing and validating analytical methods for LC-MS, GC-MS, and HPLC systems.
• Quality Control (QC) Testing: Used by pharmaceutical QC laboratories to ensure the specificity and accuracy of impurity profiling for prazepam-based medications.
• Academic Research: A valuable tool for universities and research institutes studying benzodiazepine chemistry, metabolism, and analytical techniques.

Basic Information

Product Name	3-Hydroxy-Prazepam
CAS No.	18818-61-6
Molecular Formula	C19H17ClN2O2
Molecular Weight	340.80 g/mol
Synonyms	7-Chloro-1-(cyclopropylmethyl)-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one; Desalkylflurazepam Hydroxy Metabolite; Prazepam Metabolite III; 3-OH-Prazepam; 3-Hydroxyprazepam; 1-Cyclopropylmethyl-7-chloro-3-hydroxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one
EINECS	Contact for details

Quality Control

Our 3-Hydroxy-Prazepam is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets the stringent requirements for use as a reference material. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. This material is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.