Description

Imidazenil is a high-purity benzodiazepine receptor partial agonist, distinguished for its unique pharmacological profile. This compound is critical for advanced research into anxiolytic and anticonvulsant mechanisms, offering a valuable tool for neuropharmacological studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and chemical suppliers serving the life sciences sector. Imidazenil CAS NO 151271-08-8 represents a key intermediate and reference standard for developing novel therapeutic agents.

Application

• Pharmaceutical Research & Development: Serves as a crucial reference standard and active pharmaceutical ingredient (API) intermediate in the development of novel anxiolytic and neuroactive drugs.
• Neuroscience Studies: Used as a selective pharmacological tool to investigate GABAA receptor subtypes and their role in anxiety, seizure disorders, and sedation.
• Preclinical & Clinical Trials: Employed in the formulation of dosage forms for efficacy and safety studies in animal models and human trials.
• Chemical Synthesis: Acts as a key building block or precursor in the multi-step synthesis of more complex benzodiazepine analogs and derivatives.
• Analytical & Quality Control: Provides a high-purity standard for method development, validation, and impurity profiling in HPLC, GC, and LC-MS analyses.
• Biochemical Assays: Utilized in receptor binding assays and functional studies to characterize ligand-receptor interactions and signal transduction pathways.

Basic Information

Product Name	Imidazenil
CAS No.	151271-08-8
Molecular Formula	C18H14ClN3O2
Molecular Weight	339.78 g/mol
Synonyms	4-(2-Chlorophenyl)-9-fluoro-2-[(1-methyl-1H-imidazol-5-yl)methyl]-6H-pyrido[3,4-b][1,4]diazepin-6-one; FG 10571; Imidazenilum; Ro 23-8397; 6H-Pyrido[3,4-b][1,4]diazepin-6-one, 4-(2-chlorophenyl)-9-fluoro-2-[(1-methyl-1H-imidazol-5-yl)methyl]-
EINECS	Contact for details

Quality Control

Our Imidazenil is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and stringent control of related substances and residual solvents. Certificates of Analysis (COA) detailing all test results and specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere in a freezer (-20°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.