Description

4-Amino-1-[[[(aminocarbonyl)amino]acetyl]methylamino]-3-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-1,4,5-trideoxy-6-O-methyl-L-chiro-inositol is a complex, high-purity aminoglycoside derivative with significant biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for its role as a key intermediate or reference standard.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel aminoglycoside antibiotics and other bioactive molecules.
• Biochemical Research: Used as a reference standard or probe in studies of bacterial protein synthesis inhibition and ribosomal function.
• Antibiotic Development: Acts as a core structure for the development of next-generation antibiotics targeting resistant bacterial strains.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for quality control and method validation in analytical laboratories.
• Life Science Reagent: Utilized in enzymatic and microbiological assays to study specific biochemical pathways.

Basic Information

Item	Details
Product Name	4-Amino-1-[[[(aminocarbonyl)amino]acetyl]methylamino]-3-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-1,4,5-trideoxy-6-O-methyl-L-chiro-inositol
CAS No.	83728-97-6
Molecular Formula	C₂₂H₄₄N₈O₁₀
Molecular Weight	604.64 g/mol
Synonyms	6'-N-Methylsisomicin; Antibiotic G 52; 6'-N-Methylgentamicin C1a; Sisomicin, 6'-N-methyl-; 6'-N-Methylsisomicin sulfate (salt form); Antibiotic 6640; U-57930E; 4-Amino-1-[[(carbamoylamino)acetyl]methylamino]-3-O-[2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl]-1,4,5-trideoxy-6-O-methyl-L-chiro-inositol
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent Good Manufacturing Practice (GMP) principles where applicable. Every batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR, MS), to ensure it meets exacting research and development specifications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.