Description

Gentamicin Sulfate is a broad-spectrum aminoglycoside antibiotic complex derived from *Micromonospora purpurea*. It is a critical active pharmaceutical ingredient (API) valued for its potent bactericidal activity against a wide range of Gram-negative and some Gram-positive bacteria. This compound is essential for manufacturers in the pharmaceutical and veterinary medicine sectors. Gentamicin Sulfate CAS NO 1405-41-0 is a fundamental component in formulating injectable solutions, ophthalmic preparations, and topical ointments.

Application

• Pharmaceutical API: Primary use in the manufacture of sterile injectable antibiotic formulations for systemic infections.
• Ophthalmic Preparations: Key ingredient in eye drops and ointments for treating bacterial conjunctivitis and other ocular infections.
• Veterinary Medicine: Used in formulations for treating bacterial infections in livestock, companion animals, and poultry.
• Topical Medications: Incorporated into creams and ointments for skin and wound infections.
• Research & Development: Serves as a reference standard and active component in microbiological and pharmacological research.
• Cell Culture: Sometimes used in laboratory settings as a selective agent to prevent bacterial contamination.

Basic Information

Product Name	Gentamicin Sulfate
CAS No.	1405-41-0
Molecular Formula	C21H43N5O7 • xH2SO4
Molecular Weight	Approx. 575.7 g/mol (for C1 complex)
Synonyms	Gentamycin Sulfate; Garamycin; Gentamicin Sulphate; Refobacin; Gentamicin Sulfate Salt; Gentamicin C Complex Sulfate; Gentamicin Sulfate USP; 2-Deoxystreptamine Antibiotic Complex Sulfate
EINECS	215-778-9

Quality Control

Our Gentamicin Sulfate is produced and tested to meet stringent pharmacopeial standards, including USP and EP monographs. Every batch undergoes comprehensive analytical testing for identity, potency, purity, and specific impurities. A Certificate of Analysis (COA) detailing results for assay, related substances, bacterial endotoxins, sterility (where applicable), and residual solvents is provided to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Retention time corresponds to reference
pH (1% solution)	3.5 - 5.5
Assay (HPLC, anhydrous)	590 - 630 µg/mg
Related Substances (HPLC)	Meets USP/EP requirements
Water (Karl Fischer)	≤ 15.0 %
Sulfate Content	Meets requirement
Bacterial Endotoxins	< 0.17 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.