Description

Neomycin B is a potent aminoglycoside antibiotic belonging to the neomycin complex, widely recognized for its broad-spectrum antibacterial activity. Its primary commercial value lies in its critical role as a key intermediate in pharmaceutical synthesis and as an active pharmaceutical ingredient (API) in topical formulations. This compound is essential for manufacturers in the pharmaceutical, veterinary medicine, and research sectors requiring a reliable, high-purity antimicrobial agent.

Application

• Pharmaceutical API: Used as an active ingredient in topical antibiotic ointments, creams, and eye/ear drops to treat bacterial skin and eye infections.
• Veterinary Medicine: Incorporated into animal health products for the prevention and treatment of bacterial infections in livestock and pets.
• Biochemical Research: Serves as a selective agent in cell culture media and molecular biology to study bacterial protein synthesis and antibiotic resistance mechanisms.
• Intermediate Synthesis: Acts as a crucial starting material or intermediate in the chemical synthesis of more complex antibiotic derivatives and novel drug candidates.

Basic Information

Product Name	Neomycin B
CAS No.	119-04-0
Molecular Formula	C₂₃H₄₆N₆O₁₃
Molecular Weight	614.65 g/mol
Synonyms	Framycetin; Neomycin B Sulfate (common salt form); Neomycin II; Mycifradin (brand name); Deoxyfradiomycin B; Neomycin B base; Antibiotic FRM B; O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-β-L-idopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine
EINECS	204-292-6

Quality Control

Our Neomycin B is manufactured under strict quality management systems to ensure it meets the stringent requirements of the pharmaceutical industry. Each batch is subjected to comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC. We can supply material compliant with relevant pharmacopeial standards (e.g., USP, EP) upon request. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Water (KF)	≤ 8.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Specific Rotation	+83.0° to +90.0° (c=1 in H₂O)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.