Description

4-O-[2-Amino-6-methyl-6-(methylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabino-pentopyranosyl]-N'-methyl-2-deoxy-D-streptamine is a complex, high-purity aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and study of novel antibiotic agents, particularly in addressing bacterial resistance. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require precise, well-characterized building blocks for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of next-generation aminoglycoside antibiotics.
• Research & Development: Used as a high-purity reference standard in analytical method development and pharmacokinetic studies.
• Active Pharmaceutical Ingredient (API) Synthesis: Employed in the controlled synthesis of complex antibiotic molecules targeting resistant bacterial strains.
• Biochemical Research: Serves as a tool compound for studying bacterial ribosome interaction and mechanisms of antimicrobial action.
• Quality Control: Utilized as a certified reference material (CRM) for the assay and impurity profiling of related antibiotic products.

Basic Information

Product Name	4-O-[2-Amino-6-methyl-6-(methylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabino-pentopyranosyl]-N'-methyl-2-deoxy-D-streptamine
CAS No.	74758-68-2
Molecular Formula	C26H50N6O10
Molecular Weight	606.71 g/mol
Synonyms	6'-N-Methylsisomicin; Antibiotic G 52; Antibiotic G-52; G 52 Antibiotic; G-52; Sisomicin, 6'-N-methyl-; 6'-N-Methylsisomicin; (2S,3R,4S,5S,6R)-5-Amino-2-[[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,4R,5R)-3,5-diamino-2,4,6-trihydroxy-cyclohexyl]methylamino]-2-hydroxy-cyclohexyl]oxy]-6-(aminomethyl)-3-methyl-tetrahydropyran-4-ol
EINECS	Contact for details

Quality Control

Our production of this advanced pharmaceutical intermediate adheres to stringent quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, to ensure it meets exacting specifications for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, assay, and impurity profiles. We support compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.