Description

4-O-[2-Amino-6-(dimethylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabino-pentopyranosyl]-N'-methyl-2-deoxy-D-streptamine is a complex aminoglycoside derivative of significant interest in advanced pharmaceutical research and development. This compound matters as a key intermediate or reference standard for the synthesis and analysis of novel antibiotic agents, particularly in the exploration of next-generation therapeutics targeting resistant bacterial strains. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on anti-infective drug discovery and quality control.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in drug manufacturing.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a critical building block in the multi-step synthesis of novel or modified aminoglycoside antibiotics.
• Biochemical Research: Employed in microbiological and enzymatic studies to investigate mechanisms of action, bacterial resistance, and structure-activity relationships (SAR).
• Process Development & Scale-up: Utilized in optimizing synthetic routes and purification processes for the commercial production of specialized antibiotics.
• Academic Research: A valuable tool for universities and research institutes studying carbohydrate chemistry, medicinal chemistry, and antibiotic discovery.

Basic Information

Item	Detail
Product Name	4-O-[2-Amino-6-(dimethylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabino-pentopyranosyl]-N'-methyl-2-deoxy-D-streptamine
CAS No.	74758-66-0
Molecular Formula	C26H51N5O11
Molecular Weight	585.71 g/mol
Synonyms	6'-N-Methylsisomicin; Antibiotic G 52; Antibiotic G-52; G 52 Antibiotic; Sisomicin, 6'-N-methyl-; 6'-N-Methylsisomicin; 6'-N-Methylsisomicin (8CI); (2S,3R,4S,5S,6R)-4-Amino-2-[[(1S,2S,3R,4S,6R)-4,6-diamino-3-[[(2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)oxan-2-yl]oxy]-2-hydroxycyclohexyl]oxy]-6-(dimethylamino)oxane-3,5-diol
EINECS	Contact for details

Quality Control

Our 4-O-[2-Amino-6-(dimethylamino)-2,3,4,6-tetradeoxy-α-D-erythro-hexopyranosyl]-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabino-pentopyranosyl]-N'-methyl-2-deoxy-D-streptamine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the stringent requirements for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) documenting all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.