Description

(3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-2,3,3a,4,5,8,9,10,11,11a-decahydro-10-hydroxymethyl-3-methylene-4-(2-methyl-1-oxopropoxy)-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester is a complex, high-purity diterpenoid derivative with significant synthetic utility. This compound serves as a critical advanced intermediate in the synthesis of complex natural products and novel pharmaceutical candidates, offering a pre-functionalized scaffold for further chemical elaboration. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry and total synthesis projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel diterpenoid-based drug candidates and complex bioactive molecules.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs targeting various therapeutic areas.
• Natural Product Synthesis: Serves as a pivotal intermediate in the total or semi-synthesis of complex natural products with diterpenoid skeletons.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and enzyme functions.
• Process Chemistry Development: Employed in route scouting and scale-up studies for the production of high-value fine chemicals.
• Academic Research: Used in advanced organic chemistry laboratories for teaching and research on complex multi-step synthesis.

Basic Information

Product Name	(3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-2,3,3a,4,5,8,9,10,11,11a-decahydro-10-hydroxymethyl-3-methylene-4-(2-methyl-1-oxopropoxy)-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester
CAS No.	74562-62-2
Molecular Formula	C23H32O9
Molecular Weight	452.50 g/mol
Synonyms	Methyl (3aS,4S,5S,6E,10S,11aR)-5-Acetoxy-10-(hydroxymethyl)-3-methylene-4-(2-methylpropanoyloxy)-2-oxo-3a,4,5,8,9,10,11,11a-octahydrocyclodeca[b]furan-6-carboxylate; 5-Acetoxy-10-hydroxymethyl-3-methylene-4-(2-methyl-1-oxopropoxy)-2-oxocyclodeca[b]furan-6-carboxylic acid methyl ester; A derivative of Gibberellin A12 aldehyde; Diterpenoid furan ester intermediate.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. We employ advanced analytical techniques including HPLC, NMR, and MS to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are available upon request. For custom synthesis or specific purity requirements (e.g., >95%, >98%), please contact our technical team to discuss your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture uptake. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.