Description

β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)Methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetraMethyl-12-oxo-6,10-Methanobenzocyclodecen-8- is a complex, high-purity chemical intermediate with a defined stereochemistry, making it a critical building block for advanced synthesis. This compound is valued for its precise molecular architecture, which is essential for constructing sophisticated active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in the development of novel therapeutic agents.

Application

This specialized chemical serves as a key intermediate in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex, stereospecific active pharmaceutical ingredients (APIs), particularly for oncology and anti-infective drugs.
• Research & Development: Used in medicinal chemistry for the discovery and optimization of new drug candidates, leveraging its unique functional groups for structure-activity relationship (SAR) studies.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for target molecules in pilot plant and commercial manufacturing settings.
• Bioconjugation: Potential use in creating targeted drug delivery systems or diagnostic agents due to its reactive handles for linking to biomolecules.

Basic Information

Item	Details
Product Name	β-(BenzoylaMino)-α-hydroxybenzenepropanoic Acid (αR,βS)-(1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Bis(acetyloxy)-4-[(benzoyloxy)Methyl]-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetraMethyl-12-oxo-6,10-Methanobenzocyclodecen-8-
CAS No.	932042-85-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Benzoylamino-hydroxybenzenepropanoic acid derivative; Taxoid intermediate; Paclitaxel/ Docetaxel related intermediate; (1S,3S,4S,4aR,5S,6S,8S,11R,12aS)-3,11-Diacetoxy-4-(benzoyloxymethyl)-1,2,3,4,4a,5,6,7,8,11,12,12a-dodecahydro-1,4,5,6-tetrahydroxy-9,12a,13,13-tetramethyl-12-oxo-6,10-methanobenzocyclodecen-8-yl β-(benzoylamino)-α-hydroxybenzenepropanoate; Cephalomannine derivative; 10-Deacetylbaccatin III derivative.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and chiral purity analysis, to ensure high chemical and stereochemical purity suitable for critical pharmaceutical synthesis. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.