Description

Dimethyl Acetylenedicarboxylate is a versatile and highly reactive diester of acetylenedicarboxylic acid, serving as a critical building block in advanced organic synthesis. Its value lies in its ability to act as a potent dienophile and dipolarophile, facilitating efficient Diels-Alder and 1,3-dipolar cycloaddition reactions to construct complex heterocyclic and carbocyclic frameworks. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediates: Key precursor in the synthesis of heterocyclic compounds, including pyrroles, pyrazoles, and other nitrogen-containing scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in creating novel herbicide and pesticide candidates through cycloaddition chemistry.
• Polymer & Materials Science: Serves as a monomer or cross-linking agent for developing specialty polymers with unique thermal or mechanical properties.
• Organic Synthesis Reagent: A fundamental reagent for [2+2] and [4+2] cycloadditions, Michael additions, and other carbon-carbon bond-forming reactions in academic and industrial R&D.
• Ligand & Catalyst Development: Building block for synthesizing novel chelating ligands and organometallic complexes.
• Fine Chemical Production: Intermediate in the multi-step synthesis of dyes, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	Dimethyl Acetylenedicarboxylate
CAS No.	762-42-5
Molecular Formula	C6H6O4
Molecular Weight	142.11 g/mol
Synonyms	Acetylenedicarboxylic Acid Dimethyl Ester; DMAD; Dimethyl Acetylenedicarboxylate; Dimethyl But-2-ynedioate; Methyl Acetylenedicarboxylate; 2-Butynedioic Acid, Dimethyl Ester; Acetylenedicarboxylic Acid Methyl Ester
EINECS	212-101-6

Quality Control

Our Dimethyl Acetylenedicarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (GC/HPLC) and spectroscopic methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated place, away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature: 2-8°C (refrigerated) for long-term stability.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.438 - 1.442
Density (20°C)	1.15 - 1.18 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.