Description

Ethyl-3-(Dimethylamino)-2-(Phenylcarbonyl)Prop-2-Enoate is a versatile, high-purity chemical intermediate characterized by its unique enoate structure. This compound is essential for facilitating complex synthetic transformations, particularly in the development of advanced pharmaceutical and agrochemical actives. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those requiring the introduction of a functionalized α,β-unsaturated ester moiety.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where its reactive structure serves as a precursor for heterocyclic systems.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for creating specialty chemicals, dyes, and functional materials.
• Academic & Industrial Research: A valuable reagent for methodological development in organic synthesis, including studies on Michael additions and cyclization reactions.
• Chemical Library Development: Serves as a versatile scaffold for generating diverse compound libraries in drug discovery programs through further derivatization.

Basic Information

Product Name	Ethyl-3-(Dimethylamino)-2-(Phenylcarbonyl)Prop-2-Enoate
CAS No.	66129-60-0
Molecular Formula	C₁₄H₁₇NO₃
Molecular Weight	247.29 g/mol
Synonyms	Ethyl 3-(Dimethylamino)-2-benzoylacrylate; 2-Benzoyl-3-(dimethylamino)acrylic Acid Ethyl Ester; Ethyl 2-Benzoyl-3-(dimethylamino)acrylate; 3-(Dimethylamino)-2-(phenylcarbonyl)prop-2-enoic Acid Ethyl Ester; NSC 334365; Ethyl (2E)-3-(Dimethylamino)-2-benzoyl-2-propenoate; (E)-Ethyl 3-(dimethylamino)-2-benzoylacrylate; DMABE (common abbreviation)
EINECS	Contact for details

Quality Control

Our Ethyl-3-(Dimethylamino)-2-(Phenylcarbonyl)Prop-2-Enoate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions. For long-term storage, consider using an inert atmosphere to minimize potential oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.