Description

(2E)-2-[(Acetyloxy)methyl]-4-hydroxy-2-butenoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester is a complex, high-purity chemical intermediate with significant potential in advanced organic synthesis. Its intricate molecular architecture, featuring multiple chiral centers and functional groups, makes it a valuable scaffold for constructing specialized pharmacologically active compounds. This product is primarily targeted at research and development teams within the pharmaceutical and fine chemical industries seeking to develop novel therapeutic agents or complex natural product derivatives.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the research and synthesis of novel drug candidates, particularly in oncology and anti-infective therapeutic areas.
• Advanced Organic Synthesis: Used as a key chiral precursor for constructing complex macrocyclic and polycyclic molecular frameworks in academic and industrial R&D.
• Natural Product Analog Development: Acts as a starting material or intermediate for synthesizing analogs of biologically active natural products for structure-activity relationship (SAR) studies.
• Biochemical Research: Employed in the development of specialized probes or ligands for studying enzyme mechanisms or receptor interactions.
• Process Chemistry Development: Utilized by process chemists to develop and scale up efficient synthetic routes for target molecules in pilot plants.

Basic Information

Product Name	(2E)-2-[(Acetyloxy)methyl]-4-hydroxy-2-butenoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester
CAS No.	72493-41-5
Molecular Formula	C22H30O8
Molecular Weight	422.47 g/mol
Synonyms	4-Hydroxy-2-butenoic acid 2-(acetyloxy)methyl-, (2E)-, (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester; 2-Butenoic acid, 4-hydroxy-2-[(acetyloxy)methyl]-, (2E)-, (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester; CAS 72493-41-5; 4-Hydroxy-2-butenoic acid, 2-[(acetyloxy)methyl]-, (2E)-, ester with (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-ol
EINECS	Contact for details

Quality Control

Our (2E)-2-[(Acetyloxy)methyl]-4-hydroxy-2-butenoic acid (3aR,4R,6E,9S,10E,11aR)-2,3,3a,4,5,8,9,11a-octahydro-9-hydroxy-6,10-dimethyl-3-methylene-2-oxocyclodeca[b]furan-4-yl ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, and is supplied with a detailed Certificate of Analysis (COA). We support cGMP-compliant production for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. The compound may be sensitive to moisture and hydrolysis; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.