Description

(4aR)-3,4,4aβ,5,6,7,8,8a-Octahydro-8aβ-vinyl-5β-hydroxy-7β-[(2-hydroxymethyl-1-oxo-2-propenyl)oxy]-α,4-bis(methylene)-3-oxo-1H-2-benzopyran-6α-acetic acid methyl ester is a complex, high-purity synthetic intermediate with a defined stereochemistry, crucial for advanced organic synthesis. Its intricate molecular architecture makes it a valuable building block for constructing specialized pharmacologically active compounds and fine chemicals. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and advanced material sectors who require precise, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly in the development of complex natural product analogs and therapeutic agents.
• Agrochemical Research: Used in the development of advanced, stereospecific pesticides and herbicides where specific biological activity is required.
• Fine Chemical Synthesis: Serves as a sophisticated building block for creating specialty chemicals, flavors, and fragrances with specific stereochemical properties.
• Academic & Industrial R&D: A critical reagent for methodological studies in organic chemistry, including catalysis and new bond-forming reactions.
• Material Science: Potential use as a monomer or precursor for synthesizing polymers with unique structural features.

Basic Information

Item	Details
Product Name	(4aR)-3,4,4aβ,5,6,7,8,8a-Octahydro-8aβ-vinyl-5β-hydroxy-7β-[(2-hydroxymethyl-1-oxo-2-propenyl)oxy]-α,4-bis(methylene)-3-oxo-1H-2-benzopyran-6α-acetic acid methyl ester
CAS No.	65388-17-2
Molecular Formula	C20H24O8
Molecular Weight	392.40 g/mol
Synonyms	Methyl (4aR,5S,6R,7S,8aS)-5-hydroxy-7-[(2-hydroxyacetyl)oxy]-8a-vinyl-4-methylidene-3-oxo-4,4a,5,6,7,8,8a,9-octahydro-1H-isochromene-6-carboxylate; 1H-2-Benzopyran-6α-acetic acid, 3,4,4a,5,6,7,8,8a-octahydro-8aβ-vinyl-5β-hydroxy-7β-[(2-hydroxymethyl-1-oxo-2-propenyl)oxy]-α,4-bis(methylene)-3-oxo-, methyl ester, (4aR)-; CAS 65388-17-2; Advanced Chiral Lactone Ester; Complex Octahydrobenzopyran Derivative
EINECS	Contact for details

Quality Control

Our (4aR)-3,4,4aβ,5,6,7,8,8a-Octahydro-8aβ-vinyl-5β-hydroxy-7β-[(2-hydroxymethyl-1-oxo-2-propenyl)oxy]-α,4-bis(methylene)-3-oxo-1H-2-benzopyran-6α-acetic acid methyl ester is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support custom synthesis and purification to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound may be light-sensitive and moisture-sensitive; prolonged exposure to air, light, or humidity should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area%)	≥ 98.0%
Specific Rotation [α]	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.