Description

3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 3-[7-chloro-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-, 1,1-dimethylethyl ester is a sophisticated bicyclic organic compound featuring a complex, multi-ring structure with fluorine and chlorine substituents. This molecule is of significant interest as a key pharmaceutical intermediate or advanced building block in modern drug discovery, particularly for the synthesis of targeted therapeutics. It is primarily required by research institutions and pharmaceutical development teams working on novel small molecule entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors or other targeted therapies.
• Medicinal Chemistry Research: Used as a high-value building block for constructing complex molecular architectures in drug discovery and lead optimization programs.
• Biochemical Tool Compound: Potential use in developing probes for studying biological pathways and target validation in preclinical research.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects under cGMP conditions.

Basic Information

Product Name	3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid, 3-[7-chloro-8-fluoro-2-[[(2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-, 1,1-dimethylethyl ester
CAS No.	2621932-38-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	tert-Butyl 3-(7-chloro-8-fluoro-2-(((2R,7aS)-2-fluorotetrahydro-1H-pyrrolizin-7a(5H)-yl)methoxy)pyrido[4,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate; Bicyclo[3.2.1]octane-8-carboxylic acid derivative; CAS 2621932-38-3; 3,8-Diazabicyclo[3.2.1]octane-8-carboxylic acid tert-butyl ester derivative; Fluorinated pyridopyrimidine-pyrrolizine conjugate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For pharmaceutical R&D applications, we can provide material characterized by advanced analytical techniques including HPLC, NMR, and LC-MS to meet the exacting requirements of modern drug development.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, well-ventilated place. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.