Description

3-Methylxanthine is a purine alkaloid derivative, structurally related to caffeine and theophylline, with the CAS registry number 1076-22-8. This compound serves as a valuable key intermediate and reference standard in pharmaceutical research and development. It is primarily required by pharmaceutical manufacturers, biotechnology companies, and academic research institutions engaged in metabolic studies, drug discovery, and the synthesis of more complex xanthine derivatives.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex xanthine-based drugs and bioactive molecules.
• Biochemical Research: Used as a reference standard and tool compound in studies of adenosine receptor activity, phosphodiesterase (PDE) inhibition, and purine metabolism pathways.
• Metabolite Studies: Employed in analytical laboratories for the identification and quantification of methylxanthine metabolites in biological samples.
• Academic & Contract Research: Serves as a fundamental reagent for chemical synthesis and pharmacological screening in academic and CRO (Contract Research Organization) settings.
• Analytical Standard: Provides a high-purity standard for method development and calibration in chromatographic analysis (HPLC, LC-MS).

Basic Information

Product Name	3-Methylxanthine
CAS No.	1076-22-8
Molecular Formula	C6H6N4O2
Molecular Weight	166.14 g/mol
Synonyms	3-Methyl-1H-purine-2,6-dione; 3-Methylxanthine; 3-MX; 1H-Purine-2,6-dione, 3-methyl-; 3-Methyl-3,7-dihydro-1H-purine-2,6-dione; 3-Methylhypoxanthine (obsolete); NSC 5237
EINECS	214-071-2

Quality Control

Our 3-Methylxanthine is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.